@Retrodade What kind of Repository do you use for "retropie-extra", this ?
I think this works fine (but I haven't tested yet Philips CDI games):
https://github.com/Exarkuniv/RetroPie-Extra

But I tested it with many other emulators like:
"AetherSX2 - PS2 Emulators" runs in 60Fps with my Pi5.
"Sega Supermodel 3" runs very well with my Pi5.