@StonedEdge said in RK3588s: Best performance/how to install RetroPie?:

What I meant was do I need to change anything in regards to where I point RetroPie to the games folder, which is usually stored at the directory /home/pi/RetroPie/roms

No, any RetroPie installation (regardless of platform) is using $HOME/RetroPie/roms for games by default.