@mitu

Apparently i have reinstall all package manually from section "core" (retroarch, emulationstation, retropiemenu, runcommand and latest joy2key).
Apparently retroarch and emulationstation it's recompiled from source........

When all procedure it's completed all games back to works........

If i found some core present a similar issue......... if not update it's ready i go to reinstall/recompile manually from source and see if back to works.

I have just found the issue whit Retropie_setup script and joy2key apparently not works if i launch it from emulationstation..... but i have already reply on other thread about this specific issue.

Retropie with Ubuntu 16.10 x86