@mitu thats sad, wish I knew how to code for it, as Elan Performer software takes midi-in. Great for triggering animations. Not to mention Octamed audio tracker for making music :(

Any idea what would it take to do, is it scripting or C+ coding. etc?

Some refs I have found:
https://github.com/midwan/amiberry/wiki/Serial-Port-support
and for a PC/Ami emulator:
https://www.amigaforever.com/kb/13-107
and this for Linux/Amiga:
https://mathr.co.uk/blog/2019-12-10_midi_network_between_linux_and_amiga.html