@Blackhero How are you starting RetroArch ? AFAIK, you need to start with a Disc enabled libretro core for the options to be available. This includes SegaCD, PCEngine-CD, 3DO and Saturn for the PI.
You should start a game in one of these systems and then check if the disk menus (LOAD/DUMP) show up.

@sarahsen said in Retropie 4.6 real cd-rom support:

If anyone’s interested, I can post the whole procedure.

Sure, that would be interesting. Thanks.