@shift I don't have dedicated threads for each individual lr-mess system I run, but the short answer is "more-or-less all of them".
Just to rattle off some of the ones I've tried on my Pi, with decent-to-perfect performance:
Phillips CD-i Epoch Super Cassette Vision V.tech V.Smile Various plug-and-play systems (both "official" and bootlegs) Tiger Game.com Fujitsu FM TownsOnce you get down how the core works (which admittedly is a bit of a nightmare), it's insanely versatile since it runs all the same systems as modern standalone MAME (according to the current docs, that's roughly 32,000; that link at the top is a good few years out of date). Arguably the most powerful core in all of RetroPie.