@dankcushions Thank you very much for responding. Unfortunately, none of this is working.
Here are the changes I'm making: Retroarch Menu, Input, Port 1 Binds (Mouse to 1, Trigger to fire)
If I select Quick Menu, Controls, Save Game Remap File
Quick Menu, Options, Save Game Options Files (rom name)
Neither saves the settings above.
Under Input, Port 1 Binds, there's a Save Autoconfig File option, but I'm hesitant to select that because I'm not sure exactly what it will do.